Factors controlling drug release in cross-linked poly(valerolactone) based matrices
US-2024368351-A1 · Nov 7, 2024 · US
US9109083B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9109083-B2 |
| Application number | US-201313850713-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 26, 2013 |
| Priority date | Dec 31, 2008 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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A poly(lactic acid) resin composition, including: (a) a poly(lactic acid) resin; and (b) a modifier which is in the form of nanoparticle aggregate with a particle size of less than 1000 nm and uniformly dispersed in the poly(lactic acid) resin, wherein the nanoparticle aggregate is obtained from the polycondensation of at least one metal/nonmetal alkoxide, at least one metal/nonmetal alkoxide having at least one functional group capable of reacting with the poly(lactic acid) resin, or a mixture thereof. A process for preparing a transparent and impact-resistant article from the poly(lactic acid) resin composition of the invention, and articles prepared therefrom are also provided.
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We claim: 1. A poly (lactic acid) resin composition, comprising: (a) a poly (lactic acid) resin; and (b) a modifier which is in the form of nanoparticle aggregate with a particle size of less than 1000 nm and uniformly dispersed in the poly(lactic acid) resin, wherein the nanoparticle aggregate is obtained from the polycondensation of at least one metal/nonmetal alkoxide selected from the group consisting of tetramethoxysilane (TMOS) and tetraethoxysilane (TEOS) and at least one…
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