Anti-SOD1 antibodies and uses thereof

US9109037B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9109037-B2
Application numberUS-201113882017-A
CountryUS
Kind codeB2
Filing dateOct 25, 2011
Priority dateOct 26, 2010
Publication dateAug 18, 2015
Grant dateAug 18, 2015

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  2. Abstract

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  5. First independent claim

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Abstract

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The present invention features anti-SOD1 antibodies and methods of using the antibodies for the treatment of amyotrophic lateral sclerosis (ALS) or the amelioration of symptoms associated with ALS.

First claim

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What is claimed is: 1. An isolated monoclonal antibody, or antigen binding fragment thereof, wherein said monoclonal antibody, or antigen binding fragment thereof, binds to an epitope of SOD1 protein and wherein said monoclonal antibody comprises a heavy chain variable domain and a light chain variable domain, wherein the heavy chain variable domain comprises a CDRH1, CDRH2, and CDRH3, wherein: (a) the CDRH1 comprises an amino acid sequence of SEQ ID NO:21; (b) the CDRH2 compris…

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What does patent US9109037B2 cover?
The present invention features anti-SOD1 antibodies and methods of using the antibodies for the treatment of amyotrophic lateral sclerosis (ALS) or the amelioration of symptoms associated with ALS.
Who is the assignee on this patent?
Ambrosino Donna, Babcock Gregory, Broering Teresa, and 2 more
What technology area does this patent fall under?
Primary CPC classification C07K16/40. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).