Methods and materials for identifying and treating membranous nephropathy
US-2024353404-A1 · Oct 24, 2024 · US
US9109037B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9109037-B2 |
| Application number | US-201113882017-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 25, 2011 |
| Priority date | Oct 26, 2010 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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The present invention features anti-SOD1 antibodies and methods of using the antibodies for the treatment of amyotrophic lateral sclerosis (ALS) or the amelioration of symptoms associated with ALS.
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What is claimed is: 1. An isolated monoclonal antibody, or antigen binding fragment thereof, wherein said monoclonal antibody, or antigen binding fragment thereof, binds to an epitope of SOD1 protein and wherein said monoclonal antibody comprises a heavy chain variable domain and a light chain variable domain, wherein the heavy chain variable domain comprises a CDRH1, CDRH2, and CDRH3, wherein: (a) the CDRH1 comprises an amino acid sequence of SEQ ID NO:21; (b) the CDRH2 compris…
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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