Use of ADCC-optimized antibodies for treating weak patients

US9109020B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9109020-B2
Application numberUS-201313930070-A
CountryUS
Kind codeB2
Filing dateJun 28, 2013
Priority dateJul 31, 2003
Publication dateAug 18, 2015
Grant dateAug 18, 2015

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Abstract

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The invention concerns the use of human or humanized chimeric monoclonal antibodies which are produced in selected cell lines, said antibodies bringing about a high ADCC activity as well as a high secretion of cytokines and interleukins, for treating underpopulations of so-called weak-response patients exhibiting CD16 FCGR3A-158F homozygote or FCGR3A-158V/F heterozygote polymorphism.

First claim

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The invention claimed is: 1. A method for treating haemolytic disease of the Previously Presentedborn, Sezary Syndrome, chronic myeloid leukaemias, chronic lymphoid leukaemias (CLL-B), cancer, breast cancer, conditions related to the environment, infectious diseases, chronic fatigue syndrome (CFS), parasitic infections, or viral infections, comprising: administering a composition of antibodies specific to the condition to be treated to a patient homozygous for phenylalanine in pos…

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What does patent US9109020B2 cover?
The invention concerns the use of human or humanized chimeric monoclonal antibodies which are produced in selected cell lines, said antibodies bringing about a high ADCC activity as well as a high secretion of cytokines and interleukins, for treating underpopulations of so-called weak-response patients exhibiting CD16 FCGR3A-158F homozygote or FCGR3A-158V/F heterozygote polymorphism.
Who is the assignee on this patent?
Lab Francais Du Fractionnement
What technology area does this patent fall under?
Primary CPC classification C07K16/34. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).