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Compounds, compositions, and methods for cancer therapy
US9108923B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9108923-B2 |
| Application number | US-201313946959-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 19, 2013 |
| Priority date | Jul 20, 2012 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Abstract
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Compounds including various oligomers of piperlongumine and/or piperlongumine analogues as well as certain piperlongumine analogues that exhibit improved toxicity to cancer cells are disclosed. Also provided are compositions that comprise the compounds, methods of making compositions comprising the compounds, methods of making the compounds, and the use of compounds in methods for treating cancer.
First claim
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What is claimed is: 1. A compound having the formula: wherein A is C(O) or S(O) 2 ; wherein B is alkenyl or alkynyl; wherein n=0, 1, 2, or 3; wherein R 1 is selected from the group consisting of a hydrogen, C≡C-alkyl, C≡C-cycloalkyl, C≡C-cycloalkyl halide, C≡C-phenyl, C≡C-thienyl, and a C≡C-phenyl halide wherein the halide is substituted ortho to…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9108923B2 cover?
- Compounds including various oligomers of piperlongumine and/or piperlongumine analogues as well as certain piperlongumine analogues that exhibit improved toxicity to cancer cells are disclosed. Also provided are compositions that comprise the compounds, methods of making compositions comprising the compounds, methods of making the compounds, and the use of compounds in methods for treating cancer.
- Who is the assignee on this patent?
- Broad Inst Inc, Hughes Howard Med Inst, Broad Inst, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification C07D211/86. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).