Compositions for nucleic acid delivery
US-2018369384-A1 · Dec 27, 2018 · US
US9108905B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9108905-B2 |
| Application number | US-34806409-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 2, 2009 |
| Priority date | Jan 4, 2008 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Compounds of formula (I) wherein R 1 , R 2 , R 3 , m, and Y are defined in the specification are TRPA1 antagonists. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
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The invention claimed is: 1. A pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein R 1 represent substituents of the phenyl group and each R 1 is independently alkyl, alkenyl, alkynyl, —CN, halogen, —OR a , —NO 2 , —N(R a )(R b ), —N(R b )C(O)R a , —N(R b )S(O) 2…
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