Cyclohexyl beta-hydroxy alkyl amines and medical uses thereof
US-2024390298-A1 · Nov 28, 2024 · US
US9108903B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9108903-B2 |
| Application number | US-201414167741-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 29, 2014 |
| Priority date | Jan 31, 2013 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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The invention relates to amide compounds of formula I and I′ or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels: The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain.
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We claim: 1. A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein, independently for each occurrence: Y is C or N R 1 is H, halogen, CN, or C 1 -C 6 alkyl wherein said C 1 -C 6 alkyl is substituted with 0-6 halogen and wherein up to two non-adjacent CH 2 units of said C 1 -C 6 alkyl may be replaced with —O—;…
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