Bivalent ligands for the treatment of neurological disorders
US-8946254-B2 · Feb 3, 2015 · US
Bivalent ligands for the treatment of neurological disorders
US9107954B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107954-B2 |
| Application number | US-201414568859-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 12, 2014 |
| Priority date | Jan 10, 2012 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Abstract
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Bivalent ligands that contain two pharmacophores linked through a spacer, one of which interacts with the μ-opioid receptor (MOR) and the other of which interacts with the co-receptor CC chemokine receptor 5 (CCR5), are used for the treatment of neurological disorders such as those associated with AIDS.
First claim
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We claim: 1. A method of treating neuroAIDS in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of at least one bivalent ligand of Formula I, wherein R 1 and R 2 may be the same or different, and are independently selected from: H; a saturated or unsaturated, branched or unbranched, substituted or unsubstituted c…
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- A61K47/55Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
- A61K31/485Primary
Human Necessities · mapped topic
- A61K47/481Primary
Human Necessities · mapped topic
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- What does patent US9107954B2 cover?
- Bivalent ligands that contain two pharmacophores linked through a spacer, one of which interacts with the μ-opioid receptor (MOR) and the other of which interacts with the co-receptor CC chemokine receptor 5 (CCR5), are used for the treatment of neurological disorders such as those associated with AIDS.
- Who is the assignee on this patent?
- Univ Virginia Commonwealth
- What technology area does this patent fall under?
- Primary CPC classification A61K47/55. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).