Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition
US-2015025082-A1 · Jan 22, 2015 · US
US9107952B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107952-B2 |
| Application number | US-93512907-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 5, 2007 |
| Priority date | Nov 7, 2006 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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The invention relates to novel liquid preparation comprising a substituted benzimidazol, preferably pimobendan as pharmaceutically active compound. In particular, the present invention relates to liquid preparation comprising an etherified cyclodextrin derivative, preferably in a concentration of about 20 to 70% (w/v) and said substituted benzimidazol, preferably in a concentration of about 0.005 to 0.15% (w/w).
Opening claim text (preview).
The invention claimed is: 1. A liquid preparation comprising: about 20 to 30% (w/v) of an etherified cyclodextrin derivative selected from the group consisting of alpha-, beta- and gamma-cyclodextrin ethers; and about 0.075 to 0.1% (w/v) of pimobendan or a pharmaceutically acceptable salt thereof, wherein the molar ratio of pimobendan or the pharmaceutically acceptable salt thereof to the etherified cyclodextrin derivative is about 1:47 to about 1:96. 2. Th…
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