Multi-component nanochains
US-9439966-B2 · Sep 13, 2016 · US
US9107948B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107948-B2 |
| Application number | US-201113993975-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 30, 2011 |
| Priority date | Dec 14, 2010 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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The application relates to a compound of general formula (I) below: Signal-Linker-Peptide (I) and to the uses thereof for medical imaging or diagnosis or the preparation of a composition for diagnosis of an MUC5AC pathological condition.
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The invention claimed is: 1. A compound and the pharmaceutically acceptable salts thereof, of the formula (I) Signal-Peptide or (II) Signal-Linker-Peptide, wherein: Signal is a signal entity; Linker is a chemical linking component; and Peptide is a peptide consisting of a mucin 5A (MUC5AC)-targeting peptide, wherein the MUC5AC-targeting peptide is selected from the group consisting of: a) X1-X2-X3-X4-X5-X6-X7-X8-X9 (SEQ ID No: 1), wherein: X1 is absent or cysteine or me…
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