Tetrazole derivatives
US-2024382468-A2 · Nov 21, 2024 · US
US9107945B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107945-B2 |
| Application number | US-96637710-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 13, 2010 |
| Priority date | Sep 30, 2005 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Official abstract text for this publication.
The invention relates to a pharmaceutical composition comprising an interleukin-13 antibody, more particularly a monoclonal interleukin-13 antibody, especially a human interleukin-13 monoclonal antibody, to a process for purifying said antibody and to the use of said composition in treating interleukin-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, chronic obstructive pulmonary disease, scleroderma, inflammatory bowel disease and Hodgkin's lymphoma, particularly asthma.
Opening claim text (preview).
The invention claimed is: 1. A process for purifying an IL-13 antibody comprising more than one chromatographic separation steps, wherein each of said separation steps comprises elution with a single acetate buffer comprising 50 mM sodium acetate and 85 mM sodium chloride buffered to a pH of 3.5-7.0. 2. The process of claim 1 , wherein the chromatographic separation steps are selected from the group consisting of affinity chromatography and ion exchange chromat…
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