Methods of purifying anti-interleukin-13 antibodies

US9107945B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9107945-B2
Application numberUS-96637710-A
CountryUS
Kind codeB2
Filing dateDec 13, 2010
Priority dateSep 30, 2005
Publication dateAug 18, 2015
Grant dateAug 18, 2015

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Abstract

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The invention relates to a pharmaceutical composition comprising an interleukin-13 antibody, more particularly a monoclonal interleukin-13 antibody, especially a human interleukin-13 monoclonal antibody, to a process for purifying said antibody and to the use of said composition in treating interleukin-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, chronic obstructive pulmonary disease, scleroderma, inflammatory bowel disease and Hodgkin's lymphoma, particularly asthma.

First claim

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The invention claimed is: 1. A process for purifying an IL-13 antibody comprising more than one chromatographic separation steps, wherein each of said separation steps comprises elution with a single acetate buffer comprising 50 mM sodium acetate and 85 mM sodium chloride buffered to a pH of 3.5-7.0. 2. The process of claim 1 , wherein the chromatographic separation steps are selected from the group consisting of affinity chromatography and ion exchange chromat…

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What does patent US9107945B2 cover?
The invention relates to a pharmaceutical composition comprising an interleukin-13 antibody, more particularly a monoclonal interleukin-13 antibody, especially a human interleukin-13 monoclonal antibody, to a process for purifying said antibody and to the use of said composition in treating interleukin-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, chronic…
Who is the assignee on this patent?
Hope Claire Louise, Bannister Karen, Fish Brendan Cormick, and 2 more
What technology area does this patent fall under?
Primary CPC classification A61K47/02. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).