Composition and method for the treatment of neurological diseases and cerebral injury
US-2015359762-A1 · Dec 17, 2015 · US
US9107940B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107940-B2 |
| Application number | US-201414508599-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 7, 2014 |
| Priority date | Dec 17, 2007 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing skeletal muscle deficiencies and injuries (e.g., dystrophin-deficient skeletal muscle; skeletal muscle having a contraction force deficit; skeletal muscle having a Ca 2+ imbalance; skeletal muscle having microtears).
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We claim: 1. A method of treating or reducing diaphragm skeletal muscle injury or diaphragm skeletal muscle deficiency in a subject comprising administering to a subject in need thereof a composition comprising a therapeutically effective amount of a poloxamer. 2. A methhod of claim 1 , wherein said diaphragm skeletal muscle deficiency is a skeletal muscle contraction force deficit. 3. A method of claim 1 , wherein said poloxamer is a purif…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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