Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads

US9107938B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9107938-B2
Application numberUS-201113876743-A
CountryUS
Kind codeB2
Filing dateSep 30, 2011
Priority dateSep 30, 2010
Publication dateAug 18, 2015
Grant dateAug 18, 2015

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Abstract

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Methods are provided for selecting a bacterium capable of reducing pathogenic bacterial colonization of the intestinal tract in a subject comprising selecting the bacterium capable of migrating at least 0.75 cm from the point of inoculation on motility agar after incubation for 24 hours at 37° C. or capable of migrating from the point of inoculation to a diameter of at least 1.5 cm based on the farthest colonies from the point of inoculation on motility agar after incubation for 24 hours at 37° C. Bacteria selected using the method and compositions comprising these bacteria are also provided.

First claim

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We claim: 1. A method of selecting a first bacterium capable of reducing pathogenic bacterial colonization by a second bacterium in the intestinal tract of a subject comprising: (a) selecting bacterial isolates identified as Generally Regarded as Safe bacteria by the Food and Drug Administration; (b) selecting motile bacterial isolates from the bacterial isolates of step (a); (c) selecting the bacterial isolates of step (b) that are capable of inhibiting the growth of Campylobacte…

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What does patent US9107938B2 cover?
Methods are provided for selecting a bacterium capable of reducing pathogenic bacterial colonization of the intestinal tract in a subject comprising selecting the bacterium capable of migrating at least 0.75 cm from the point of inoculation on motility agar after incubation for 24 hours at 37° C. or capable of migrating from the point of inoculation to a diameter of at least 1.5 cm based on the…
Who is the assignee on this patent?
Donoghue Daniel James, Donoghue Ann Marian, Univ Arkansas, and 1 more
What technology area does this patent fall under?
Primary CPC classification A61K35/74. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).