Antagonists of GRASP55 for use as a medicament

US9107936B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9107936-B2
Application numberUS-201213983417-A
CountryUS
Kind codeB2
Filing dateFeb 2, 2012
Priority dateFeb 2, 2011
Publication dateAug 18, 2015
Grant dateAug 18, 2015

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Abstract

Official abstract text for this publication.

The present invention concerns antagonists of the Golgi reassembly-stacking protein of 55 k Da (Grasp55), for use as a medicament, in particular for use in the treatment of cell adhesion molecules implicated diseases, notably, MCAM or JAMs implicated diseases. According to some embodiments, said antagonists of the Golgi reassembly-stacking protein of 55 k Da (Grasp55) may be used in the treatment of cancer, metastases, and inflammatory diseases. The present invention further provides methods for screening for compounds liable of treating or preventing such diseases.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for treating a patient suffering from a JAM-A or JAM-C implicated disease said method comprising the step of administering an effective amount of an antagonist of the Golgi reassembly-stacking protein of 55 kDa (Grasp55) to an individual in need thereof. 2. The method of claim 1 , wherein said JAM-A or JAM-C implicated disease is selected from the group consisting of cancer and an inflammatory disease. 3…

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What does patent US9107936B2 cover?
The present invention concerns antagonists of the Golgi reassembly-stacking protein of 55 k Da (Grasp55), for use as a medicament, in particular for use in the treatment of cell adhesion molecules implicated diseases, notably, MCAM or JAMs implicated diseases. According to some embodiments, said antagonists of the Golgi reassembly-stacking protein of 55 k Da (Grasp55) may be used in the treatme…
Who is the assignee on this patent?
Aurrand-Lions Michel, Zarubica Ana, Inst Nat Sante Rech Med, and 1 more
What technology area does this patent fall under?
Primary CPC classification A61K31/713. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).