Pyrimidinecarboxamide derivatives

Patent metadata

Field	Value
Publication number	US-9107922-B2
Application number	US-201113808508-A
Country	US
Kind code	B2
Filing date	Jul 13, 2011
Priority date	Jul 16, 2010
Publication date	Aug 18, 2015
Grant date	Aug 18, 2015

Abstract

This disclosure relates to novel HIV integrase inhibitors their derivatives, pharmaceutically acceptable salts thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions in methods of treating HIV infections.

First claim

I claim:

1. A compound of Formula I-A:

or a pharmaceutically acceptable salt thereof, wherein:
each of R 1 , R 2a , R 2b , and R 3 is independently selected from —CH 3 , —CDH 2 , —CD 2 H, and —CD 3 ;
Y 1 and Y 2 are each independently selected from H and D;
R 4 is selected from:…

Assignees

• Tung Roger
• Concert Pharmaceuticals Inc

Inventors

• Tung Roger

Classifications

• A61P31/18

  Human Necessities · mapped topic

• A61K31/506 Primary

  Human Necessities · mapped topic

• A61K45/06

  Human Necessities · mapped topic

• C07D413/12

  Chemistry & Metallurgy · mapped topic

• C07B59/002

  Chemistry & Metallurgy · mapped topic