Inducible tissue constructs and uses thereof
US-2024287463-A1 · Aug 29, 2024 · US
Isolated liver stem cells
US9107910B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107910-B2 |
| Application number | US-201414294886-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 3, 2014 |
| Priority date | Dec 21, 2005 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Abstract
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Isolated liver progenitor stem cells and cell populations of isolated liver progenitor stem cells are disclosed. The progenitor stem cells originate from adult liver, especially human adult liver. The isolated progenitor stem cells have uses in medicine, hepatology, inborn errors of liver metabolism transplantation, infectious diseases and liver failure. Methods of isolating these cells and their culture is described. The isolated cells are characterized before and after differentiation. Their use for transplantation and as animal models of human disease, toxicology and pharmacology is disclosed.
First claim
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What is claimed is: 1. An isolated human progenitor or stem cell originated from human adult liver characterized in that: (a) the isolated human progenitor or stem cell expresses at least the mesenchymal markers vimentin and α-smooth muscle actin (ASMA), (b) the isolated human progenitor or stem cell expresses the hepatocyte marker albumin (ALB), (c) the isolated human progenitor or stem cell is negative for cytokeratin-19 (CK-19), and (d) the isolated human progenitor or st…
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Frequently asked questions
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- What does patent US9107910B2 cover?
- Isolated liver progenitor stem cells and cell populations of isolated liver progenitor stem cells are disclosed. The progenitor stem cells originate from adult liver, especially human adult liver. The isolated progenitor stem cells have uses in medicine, hepatology, inborn errors of liver metabolism transplantation, infectious diseases and liver failure. Methods of isolating these cells and the…
- Who is the assignee on this patent?
- Univ Catholique Louvain, Univ Catholique Louvain
- What technology area does this patent fall under?
- Primary CPC classification A61K35/407. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).