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Methods and compositions for imaging cancer cells
US9107895B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107895-B2 |
| Application number | US-84366410-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 26, 2010 |
| Priority date | Jul 24, 2009 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Abstract
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Disclosed are compositions comprising nanoparticles and uses thereof. Such nanoparticles include gold nanoparticles conjugated to glucose or a glucose derivative, which are useful as contrast agents in imaging methods such as computed tomography (CT). Nanoparticles disclosed herein are useful in imaging various cells, tissues, and organs, and are particularly useful in imaging tumors and tumor cells in vitro and in vivo.
First claim
Opening claim text (preview).
What is claimed is: 1. A composition comprising: a gold nanoparticle; a glucose derivative comprising 2-Deoxy-D-Glucose attached to the gold nanoparticle, wherein the 2-Deoxy-D-Glucose is attached to the gold nanoparticle at the 2-Carbon site of the 2-Deoxy-D-Glucose. 2. The composition of claim 1 , where the 2-Deoxy-D-Glucose is attached to the gold nanoparticle by a mercapto group. 3. A kit comprising: a container having a sterile…
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Human Necessities · mapped topic
Operations & Transport · mapped topic
- A61K31/7004Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9107895B2 cover?
- Disclosed are compositions comprising nanoparticles and uses thereof. Such nanoparticles include gold nanoparticles conjugated to glucose or a glucose derivative, which are useful as contrast agents in imaging methods such as computed tomography (CT). Nanoparticles disclosed herein are useful in imaging various cells, tissues, and organs, and are particularly useful in imaging tumors and tumor …
- Who is the assignee on this patent?
- Aydogan Bulent, Rajh Tijana, Univ Chicago, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification A61K31/7004. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).