G-protein-coupled receptor regulators and methods of use thereof
US-2024417378-A1 · Dec 19, 2024 · US
US9107893B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107893-B2 |
| Application number | US-201414301756-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 11, 2014 |
| Priority date | Dec 15, 2009 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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The present invention relates to methods, pharmaceutical compositions and kits for use in the treatment of Adult T-cell leukemia/lymphoma. More particularly, the present invention relates to a combination of an interferon, an arsenic compound and a reverse transcriptase inhibitor for the treatment of Adult T-cell leukemia/lymphoma.
Opening claim text (preview).
The invention claimed is: 1. A method of eradicating leukemia initiating cells in a subject affected with adult T-cell leukemia/lymphoma, comprising administering to said adult a dose from 3-5 million international units (MIU) per day of interferon-alpha, a dose from 10-15 mg per day of arsenic trioxide, and a dose from 600 to 1000 mg per kg of body weight per day of zidovudine. 2. The method according to claim 1 wherein said arsenic trioxide is administered b…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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