Glyconjugate Vaccines
US-2024382585-A1 · Nov 21, 2024 · US
US9107872B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107872-B2 |
| Application number | US-57026609-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 30, 2009 |
| Priority date | Dec 22, 2005 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various conjugated capsular saccharides from different S. pneumoniae serotypes conjugated to 2 or more different carrier proteins, where the composition comprises serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT) or CRM197, optionally wherein 19F is the only saccharide in the composition conjugated to diphtheria toxoid (DT) or CRM197.
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The invention claimed is: 1. A Streptococcus pneumoniae immunogenic composition comprising 10 or more capsular saccharides from at least 10 different S. pneumoniae serotypes, each capsular saccharide conjugated to a carrier protein, wherein the composition comprises at least three different carrier proteins, wherein the composition comprises: serotype 19F capsular saccharide conjugated to diphtheria toxoid (DT); serotype 18C capsular saccharide conjugated to tetanus toxoid (TT)…
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