Cellular Adjuvants for Viral Infection
US-2024299521-A1 · Sep 12, 2024 · US
Vaccine formulations comprising saponin-containing adjuvants
US9107859B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107859-B2 |
| Application number | US-87863010-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 9, 2010 |
| Priority date | Sep 10, 2009 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Abstract
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The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified (crude extracts) or minimally purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and, in particular, an immunogen selected from the group consisting of an inactivated pathogen, an attenuated pathogen, a subunit, a recombinant expression vector, and a plasmid or combinations thereof.
First claim
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What is claimed is: 1. A safe and effective stable immunological injectable oil-in-water (O/W) emulsion, wherein the emulsion is effective for eliciting an immunologic response in a vaccinate, comprising: (i) an aqueous solution comprising about 60 μg of whole inactivated porcine circovirus 2 (PCV2) virus per dose; (ii) an aqueous solution comprising a saponin in the amount of about 0.7 mg/dose to about 1.3 mg/dose; wherein the saponin consists of an anion-exchange column purifi…
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- What does patent US9107859B2 cover?
- The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified (crude extracts) or minimally purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and, in particular, an…
- Who is the assignee on this patent?
- Detraz Noel Joseph Francois, Rigaut Guillaume, Merial Inc
- What technology area does this patent fall under?
- Primary CPC classification A61K39/39. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).