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Obtaining data for automatic glaucoma screening, and screening and diagnostic techniques and systems using the data
US9107617B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107617-B2 |
| Application number | US-201013510290-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 16, 2010 |
| Priority date | Nov 16, 2009 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Abstract
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A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode. Texture analysis is performed on the fundus images to classify them based on their quality, and only images which are determined to meet a quality criterion are subjected to an analysis to determine if they exhibit glaucoma indicators. Also, the images are put into a standard format. The system may include estimating the position of the optic cup by combining results from multiple optic cup segmentation techniques. The system may include estimating the position of the optic disc by applying edge detection to the funds image, excluding edge points that are unlikely to be optic disc boundary points, and estimating the position of an optic disc by fitting an ellipse to the remaining edge points.
First claim
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What is claimed is: 1. A method of identifying an optic cup in a fundus image, the method comprising: performing a plurality of optic cup identification algorithms to obtain respective preliminary estimates of a position of the optic cup; estimating a centre of the optic cup; for each of a number of angular positions about the centre of the optic cup combining the estimates of the position of the optic cup to form an improved estimate of the position of the optic cup, by a fus…
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- A61B3/0025Primary
Human Necessities · mapped topic
Physics · mapped topic
Human Necessities · mapped topic
Physics · mapped topic
Human Necessities · mapped topic
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- What does patent US9107617B2 cover?
- A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In comb…
- Who is the assignee on this patent?
- Liu Jiang, Zhang Zhuo, Wong Wing Kee Damon, and 13 more
- What technology area does this patent fall under?
- Primary CPC classification A61B3/0025. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).