Antibiotic-free plasmids
US-9217153-B2 · Dec 22, 2015 · US
Method for producing heterologous protein using yeast with disruption of VPS gene
US9102969B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9102969-B2 |
| Application number | US-201214004223-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 7, 2012 |
| Priority date | Mar 11, 2011 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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Abstract
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An object of the present invention it to improve the secretion productivity of a heterologous protein in a methanol-assimilating yeast. The present invention provides a method for producing a heterologous protein, characterized by comprising using a methanol-assimilating yeast with disruption of the VPS gene as a host for secretory production of the heterologous protein.
First claim
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The invention claimed is: 1. A method for producing a heterologous protein, characterized by comprising using methanol-assimilating yeast with simultaneous disruptions of the vacuolar protein sorting (VPS) gene and the vacuolar protease B (PRB1) gene as a host for secretory production of the heterologous protein, wherein the VPS gene is at least one gene selected from the group consisting of VPS8, and VPS15. 2. The method according to claim 1 , wherein the meth…
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- What does patent US9102969B2 cover?
- An object of the present invention it to improve the secretion productivity of a heterologous protein in a methanol-assimilating yeast. The present invention provides a method for producing a heterologous protein, characterized by comprising using a methanol-assimilating yeast with disruption of the VPS gene as a host for secretory production of the heterologous protein.
- Who is the assignee on this patent?
- Nishiyama Tozo, Sakai Yasuyoshi, Kaneka Corp
- What technology area does this patent fall under?
- Primary CPC classification C12P21/00. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).