Cellulose-synthase-like enzymes and uses thereof
US-2024315192-A1 · Sep 26, 2024 · US
US9102948B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9102948-B2 |
| Application number | US-94195007-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 18, 2007 |
| Priority date | Nov 17, 2006 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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MPO1 and MPO2 can be regulated for either decreasing or increasing alkaloid levels in plants, in particular in Nicotiana plants. In particular, suppressing or overexpressing one or more of MPO1 and MPO2 may be used to decrease or increase nicotine and nicotinic alkaloid levels in tobacco plants. Suppression or overexpression of one or more of MPO1 and MPO2 may be used in combination with modification of expression of other genes encoding enzymes on the nicotinic alkaloid biosynthetic pathway such as A622, NBB1, PMT, and QPT.
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What is claimed is: 1. A nucleic acid construct comprising a nucleotide sequence selected from the group consisting of: (a) the nucleotide sequence set forth in SEQ ID NO: 3; and (b) a nucleotide sequence that encodes a polypeptide having the amino acid sequence set forth in SEQ ID NO: 4; wherein the nucleotide sequence is operatively linked in sense, antisense, or inverted repeat orientation to a heterologous promoter. 2. A nucleic acid construct, compri…
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