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Method of effecting de-differentiation of a cell
US9102920B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9102920-B2 |
| Application number | US-99128408-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 21, 2008 |
| Priority date | May 6, 2008 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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Abstract
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The invention provides a method of effecting de-differentiation of an at least partially differentiated cell or of maintaining pluripotency and/or self-renewing characteristics of an undifferentiated cell. The method comprises increasing the amount or the activity of an Err protein, or a functional fragment thereof, in the cell.
First claim
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What is claimed is: 1. A method of reprogramming a cell to produce a cell with pluripotency and self-renewing characteristics, the method comprising increasing the amount or activity of an estrogen-related (Err) protein, or a functional fragments thereof, Oct4, Sox2, and c-Myc in a cultured cell, wherein the cultured cell is a cultured somatic cell, a cultured precursor cell, or a cultured partially differentiated stem cell and wherein the Err protein is one of an Esrrb protein and…
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- C12N5/0696Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US9102920B2 cover?
- The invention provides a method of effecting de-differentiation of an at least partially differentiated cell or of maintaining pluripotency and/or self-renewing characteristics of an undifferentiated cell. The method comprises increasing the amount or the activity of an Err protein, or a functional fragment thereof, in the cell.
- Who is the assignee on this patent?
- Feng Bo, Jiang Jianming, Ng Huck Hui, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification C12N5/0696. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).