3D trophoblast matrix for preparing organ-specific stem cells

US9102914B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9102914-B2
Application numberUS-201113257949-A
CountryUS
Kind codeB2
Filing dateFeb 3, 2011
Priority dateFeb 3, 2011
Publication dateAug 11, 2015
Grant dateAug 11, 2015

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Abstract

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This disclosure relates generally to methods, apparatuses, and cellular compositions and cellular products that use a unique trophoblast-containing 3D matrix as a compartmental chamber for growing embryoid bodies that can be induced to differentiate into organ-specific cell types.

First claim

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What is claimed is: 1. A method for creating lineage-specific stem cells, comprising: a) seeding human embryonic stem cells (hESCs) into a trophoblast-containing three-dimensional matrix; b) growing an embryoid body from the human embryonic stem cells within the trophoblast-containing matrix; c) transferring the trophoblast-matrix containing the embryoid body from step (b) into a new culture medium that contains at least one differentiation agent that causes the ES cells to be…

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What does patent US9102914B2 cover?
This disclosure relates generally to methods, apparatuses, and cellular compositions and cellular products that use a unique trophoblast-containing 3D matrix as a compartmental chamber for growing embryoid bodies that can be induced to differentiate into organ-specific cell types.
Who is the assignee on this patent?
Gu Yansong, Empire Technology Dev Llc
What technology area does this patent fall under?
Primary CPC classification C12N5/06. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).