MK2 inhibitors

US9102676B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9102676-B2
Application numberUS-201414297167-A
CountryUS
Kind codeB2
Filing dateJun 5, 2014
Priority dateDec 14, 2009
Publication dateAug 11, 2015
Grant dateAug 11, 2015

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

The present invention relates to compounds of general Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used in the treatment of immune, autoimmune, inflammatory diseases, cardiovascular diseases, infectious diseases, bone resorption disorders, neurodegenerative diseases or proliferative diseases.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of inhibiting MK2 activity comprising the step of contacting a cell with a compound selected from the group consisting of: 2′-(2-(benzofuran-2-yl)pyrimidin-4-yl)-5′,6′-dihydrospiro[piperidine-4,7′-pyrrolo[3,2-c]pyridin]-4′(1H)-one; 2′-(2′-amino-2,5′-bipyrimidin-4-yl)-5′,6′-dihydrospiro[piperidine-4,7′-pyrrolo[3,2-c]pyridin]-4′(1′H)-one; 2′-(2-(5-methoxypyridin-3-yl)pyrimidin-4-yl)-5′,6′-dihydrospiro[piperidine-4,7′-pyrrolo[3,2-c]pyridin]-4…

Assignees

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  • Human Necessities · mapped topic

  • Human Necessities · mapped topic

  • Human Necessities · mapped topic

  • Human Necessities · mapped topic

  • Human Necessities · mapped topic

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Frequently asked questions

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What does patent US9102676B2 cover?
The present invention relates to compounds of general Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used in the treatment of immune, autoimmune, inflammatory diseases, cardiovascular diseases, infectious diseases, bone resorption disorders, neurodegenerative diseases or proliferative diseases.
Who is the assignee on this patent?
Merck Sharp & Dohme
What technology area does this patent fall under?
Primary CPC classification C07D471/20. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).