Heterocyclic modulators of lipid synthesis
US-2024400552-A1 · Dec 5, 2024 · US
US9102671B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9102671-B2 |
| Application number | US-201214000578-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 23, 2012 |
| Priority date | Feb 25, 2011 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TRK kinase activity. wherein: A is X 1 is CH or N;
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We claim: 1. A compound of Formula (I): wherein: A is X 1 is CH or N; R 1 is —C(O)NH 2 , —C(O)N(R 7 ) 2 , —C(O)N(R 8 ) 2 , —NR 7 C(O)R 8 , —NR 7 C(O)N(R 7 ) 2 , —NR 7 C(O)N(R 8 ) 2 , —NR 7 C(O)N(R 9 ) 2 ; —C(O)OR 7 , —NR 7 C(O)O…
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