Asgpr-binding compounds for the degradation of extracellular proteins
US-2024424108-A1 · Dec 26, 2024 · US
US9102669B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9102669-B2 |
| Application number | US-201214363051-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 5, 2012 |
| Priority date | Dec 6, 2011 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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The present invention is directed to novel piperidinyl-pyridazinyl derivatives, pharmaceutical compositions containing them and their use as inhibitors of SCD1, useful in the treatment of obesity, type-II diabetes and other related metabolic disorders.
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We claim: 1. A compound of formula (I) wherein R 1 is selected from the group consisting of a is an integer from 0 to 3; each R 2 is independently selected from the group consisting of halogen, C 1-4 alkyl, C 1-4 alkoxy, halogenated C 1-2 alkyl…
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