Sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1H-imidazol-4-yl)-propionic acid

US9102657B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9102657-B2
Application numberUS-201214359734-A
CountryUS
Kind codeB2
Filing dateNov 22, 2012
Priority dateNov 25, 2011
Publication dateAug 11, 2015
Grant dateAug 11, 2015

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Abstract

Official abstract text for this publication.

The invention relates to a sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1H-imidazol-4-yl)-propionic acid, and to a sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1H-imidazol-4-yl)-propionic acid which is in a crystalline form or in at least partially crystalline form, as well as a process for the preparation of the same, methods of using such salt to treat subjects suffering from conditions which can be ameliorated by the administration of an inhibitor of the enzyme TAFIa (activated thrombin-activatable fibrinolysis inhibitor).

First claim

Opening claim text (preview).

The invention claimed is: 1. A Sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1H-imidazol-4-yl)-propionic acid as a dihydrate of the structure: 2. The Sodium salt according to claim 1 wherein the crystalline salt exhibits in an X-ray powder diffraction pattern measured in transmission with CuKα 1 radiation at room temperature a characteristic r…

Assignees

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Classifications

  • C07D401/06Primary

    Chemistry & Metallurgy · mapped topic

  • Human Necessities · mapped topic

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What does patent US9102657B2 cover?
The invention relates to a sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1H-imidazol-4-yl)-propionic acid, and to a sodium salt of (R)-3-[6-amino-pyridin-3-yl]-2-(1-cyclohexyl-1H-imidazol-4-yl)-propionic acid which is in a crystalline form or in at least partially crystalline form, as well as a process for the preparation of the same, methods of using such salt to treat subjects s…
Who is the assignee on this patent?
Sanofi Sa
What technology area does this patent fall under?
Primary CPC classification C07D401/06. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).