Compounds for stabilizing ryanodine receptors from aberrant levels of calcium release

US9102645B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9102645-B2
Application numberUS-201414213614-A
CountryUS
Kind codeB2
Filing dateMar 14, 2014
Priority dateMar 15, 2013
Publication dateAug 11, 2015
Grant dateAug 11, 2015

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Abstract

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Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.

First claim

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We claim: 1. A method for treating a neurological or neurodegenerative disorder in a subject, wherein the neurological or neurodegenerative disorder is Alzheimer's disease or traumatic brain injury, comprising administering to the subject an effective amount of a compound selected from the group consisting of:…

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What does patent US9102645B2 cover?
Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injur…
Who is the assignee on this patent?
Univ Rosalind Franklin Medicine & Science
What technology area does this patent fall under?
Primary CPC classification C07D307/52. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).