Mitotic kinesin inhibitors and methods of use thereof

US9102639B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9102639-B2
Application numberUS-201314099276-A
CountryUS
Kind codeB2
Filing dateDec 6, 2013
Priority dateOct 19, 2004
Publication dateAug 11, 2015
Grant dateAug 11, 2015

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  2. Abstract

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  5. First independent claim

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Abstract

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This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.

First claim

Opening claim text (preview).

What is claimed is: 1. A compound of the Formula: and solvates, resolved enantiomers, diastereomers, racemic mixtures and pharmaceutically acceptable salts thereof, wherein: X is S, R is Z—NR 2 R 3 , Z—OH, or Z—OP(═O)(OR a )(OR a ); R 1 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, saturated or partially unsaturated cycloalkyl, saturated or partia…

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What does patent US9102639B2 cover?
This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.
Who is the assignee on this patent?
Array Biopharma Inc
What technology area does this patent fall under?
Primary CPC classification C07D285/12. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).