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Process for the preparation of retigabine
US9102593B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9102593-B2 |
| Application number | US-201213980210-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 16, 2012 |
| Priority date | Jan 18, 2011 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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Abstract
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This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.
First claim
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The invention claimed is: 1. A process for the production of 2-ethoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene (a compound of formula (I)) or a salt thereof: which comprises reacting 4-(4-fluorobenzylamino)-2-nitroaniline (the compound of formula (II)) with…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
- C07C269/06Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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- What does patent US9102593B2 cover?
- This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.
- Who is the assignee on this patent?
- Fitzgerald Russ N, Millar Alan, Toczko Jennifer Fell, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification C07C269/06. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).