Atherosclerosis-targeted liposome nanocarrier delivery system and preparation method therefor
US-2024424132-A1 · Dec 26, 2024 · US
US9102591B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9102591-B2 |
| Application number | US-201314050431-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 10, 2013 |
| Priority date | Oct 12, 2012 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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The present invention is directed to benzamide containing compounds which inhibit the P2X7 Receptor.
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What is claimed: 1. A compound of formula I wherein R 1 is pyridyl, pyrazinyl, pyridazinyl, or pyrimidyl, each of which is optionally substituted with one or more C 1-6 alkyl, halogen, hydroxy, C 1-6 hydroxyalkyl, C 1-4 fluoroalkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, C 1-4 fluoroalkoxy, cyano or —SO 2 R 8 ; wherein R 2 is C 3-6 cycloalkyl, C 3-6 cyclohetalkyl,…
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