Methods and compositions for cancer treatment
US-2024424094-A1 · Dec 26, 2024 · US
Material and methods for treating or preventing HER-3 associated diseases
US9101760B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9101760-B2 |
| Application number | US-94476410-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 12, 2010 |
| Priority date | Nov 13, 2009 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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Abstract
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Described herein are materials and methods for treating subjects having a HER-3 associated disease, by administering a first agent that binds to HER-3, in combination with a second agent that binds and/or inhibits another member of the HER family. The first and the second agent may be a biologic, such as an antigen-binding protein, or a small molecular tyrosine kinase inhibitor, for example.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of treating a cancer associated with HER-3 in a subject, comprising administering to the subject a first agent and a second agent, wherein said first agent is an isolated binding protein which binds to HER-3, comprising: (a) a heavy chain amino acid sequence that comprises a CDRH1 having the sequence of SEQ ID NO:236, a CDRH2 having the sequence of SEQ ID NO:258, and a CDRH3 having the sequence of SEQ ID NO:283; and a light chain amino acid sequen…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US9101760B2 cover?
- Described herein are materials and methods for treating subjects having a HER-3 associated disease, by administering a first agent that binds to HER-3, in combination with a second agent that binds and/or inhibits another member of the HER family. The first and the second agent may be a biologic, such as an antigen-binding protein, or a small molecular tyrosine kinase inhibitor, for example.
- Who is the assignee on this patent?
- Hettmann Thore, Freeman Daniel J, Radinsky Robert, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification A61K39/39558. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).