Compositions including triciribine and taxanes and methods of use thereof

US9101641B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9101641-B2
Application numberUS-201314091073-A
CountryUS
Kind codeB2
Filing dateNov 26, 2013
Priority dateMar 29, 2004
Publication dateAug 11, 2015
Grant dateAug 11, 2015

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

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This application relates to combination therapies including triciribine and related compounds and taxanes and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.

First claim

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What is claimed is: 1. A method for treating a subject having a tumor or cancer, which tumor or cancer overexpresses AKT kinase comprising: (i) determining whether the subject has a tumor or cancer that overexpresses AKT kinase; (ii) if said subject has a tumor or cancer that overexpresses AKT kinase, a. administering to said subject: i. 45 mg/m 2 or less of at least one compound of formula I selected from the group consisting of the following compounds:…

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What does patent US9101641B2 cover?
This application relates to combination therapies including triciribine and related compounds and taxanes and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.
Who is the assignee on this patent?
Univ South Florida
What technology area does this patent fall under?
Primary CPC classification A61K31/7064. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).