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Methods of treating inflammation with compositions comprising lecithin oils and NSAIDS for protecting the gastrointestinal tract and providing enhanced therapeutic activity
US9101637B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9101637-B2 |
| Application number | US-88390210-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 16, 2010 |
| Priority date | Dec 19, 2000 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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Abstract
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A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulsion for internal, oral, direct or topical administration.
First claim
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I claim: 1. A method of reducing a GI toxic effect of a non-steroidal anti-inflammatory drug (NSAID) in a subject who ingests the NSAID, comprising administering the NSAID to the subject as an NSAID-in-oil suspension that comprises lecithin oil and an NSAID, wherein the lecithin oil consists of soy lecithin components in sunflower oil and has about 33 to about 40 wt. % of phosphatidylcholine (PC), about 26 to about 31 wt. % triglycerides, about 8 to about 13 wt. % free fatty acids…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US9101637B2 cover?
- A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, p…
- Who is the assignee on this patent?
- Lichtenberger Lenard M, Univ Texas
- What technology area does this patent fall under?
- Primary CPC classification A61K47/24. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).