Methods of treating or preventing insulin resistance and associated diseases and conditions

US9101601B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9101601-B2
Application numberUS-201314370140-A
CountryUS
Kind codeB2
Filing dateJan 3, 2013
Priority dateJan 9, 2012
Publication dateAug 11, 2015
Grant dateAug 11, 2015

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  2. Abstract

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  4. Key dates

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  5. First independent claim

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Abstract

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Disclosed are methods of treating an animal for insulin resistance and associated diseases or conditions, activating the transcriptional activity of heat shock factor 1 (HSF1), or inducing the expression of heat shock protein 70 (HSP70) in an animal in need thereof, wherein the methods involve administering an effective amount of one or more compounds of formula (I) or an epimer thereof, wherein Ar, and R 1 -R 6 are described herein. Examples of diseases or conditions associated with insulin resistance include diabetes, obesity, inflammation, metabolic syndrome, polycystic ovary disease, arteriosclerosis, non-alcoholic fatty liver disease, reproductive abnormality in a female, and growth abnormality.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of treating an animal for insulin resistance or type II diabetes comprising administering to the animal an effective amount of a compound of formula (I): or an epimer thereof; wherein Ar is an aryl group, optionally substituted with one or more substituents selected from the group consisting of C 1 -C 6 alkyl, C 1 -C 6 hydroxyalkyl…

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What does patent US9101601B2 cover?
Disclosed are methods of treating an animal for insulin resistance and associated diseases or conditions, activating the transcriptional activity of heat shock factor 1 (HSF1), or inducing the expression of heat shock protein 70 (HSP70) in an animal in need thereof, wherein the methods involve administering an effective amount of one or more compounds of formula (I) or an epimer thereof, wherei…
Who is the assignee on this patent?
Us Health
What technology area does this patent fall under?
Primary CPC classification A61K31/343. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).