Nanoparticulate megestrol formulations
US-2015056286-A1 · Feb 26, 2015 · US
US9101540B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9101540-B2 |
| Application number | US-87862304-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 29, 2004 |
| Priority date | Apr 12, 2002 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm.
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We claim: 1. A pharmaceutical composition in the form of a stable oral suspension comprising: (i) nanoparticulate megestrol acetate particles having an effective average particle size of less than 150 nm in water at a concentration of about 115 mg to about 135 mg megestrol acetate per ml of said composition; and (ii) at least one surface stabilizer adsorbed on the surface of the megestrol acetate particles, wherein upon administration, about 575 mg to about 675 mg of said comp…
Human Necessities · mapped topic
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