Cooperia vaccine
US-2018369349-A1 · Dec 27, 2018 · US
Diagnostic assays and methods of use for detection of filarial infection
US9068993B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9068993-B2 |
| Application number | US-201113882850-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 31, 2011 |
| Priority date | Nov 4, 2010 |
| Publication date | Jun 30, 2015 |
| Grant date | Jun 30, 2015 |
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Abstract
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The polynucleotide encoding the antigen Wb123 from the filarial nematode Wuchereria bancrofti , the major causative organism of lymphatic filariasis is provided, along with the polypeptide encoded by the polynucleotide. Methods for making the WM23 antigen, recombinant vectors encoding the Wb123 polynucleotide, and methods of detection of the Wb123 antigen through luciferase immunoprecipitation, ELISA and other detection systems are also provided.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for detecting presence of antibodies to Wuchereria bancrofti or Brugia malayi infective larvae (L3) in a sample, the method comprising: a) contacting the sample with a first binding reagent which comprises a fusion protein having a reporter domain and a binding domain, the binding domain comprising Wb123 antigen, and forming an immunocomplex, wherein the Wb123 antigen is encoded by the polynucleotide sequence of SEQ ID NO: 1; b) contacti…
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- C07K14/4354Primary
Chemistry & Metallurgy · mapped topic
Physics · mapped topic
- G01N33/6893Primary
Physics · mapped topic
Physics · mapped topic
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- What does patent US9068993B2 cover?
- The polynucleotide encoding the antigen Wb123 from the filarial nematode Wuchereria bancrofti , the major causative organism of lymphatic filariasis is provided, along with the polypeptide encoded by the polynucleotide. Methods for making the WM23 antigen, recombinant vectors encoding the Wb123 polynucleotide, and methods of detection of the Wb123 antigen through luciferase immunoprecipitation…
- Who is the assignee on this patent?
- Nutman Thomas B, Fink Doran, Kubofcik Joseph, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification C07K14/4354. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 30 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).