Droplet bilayer formation using throughput liquid handling techniques

US9068280B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9068280-B2
Application numberUS-201113520339-A
CountryUS
Kind codeB2
Filing dateJan 5, 2011
Priority dateJan 5, 2010
Publication dateJun 30, 2015
Grant dateJun 30, 2015

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Abstract

Official abstract text for this publication.

The invention relates to methods and devices for forming and measuring lipid bilayers, for example, by joining lipid monolayers that self-assemble at the interface of aqueous and organic phases using sessile aqueous droplets in contact with a measurement electrode. At least one of the aqueous solution, the lower aqueous phase, and/or the upper organic phase comprise lipids. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

First claim

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What is claimed is: 1. A method for forming a lipid bilayer, comprising the steps of: a) providing a droplet electrode with a tip having at least a sessile droplet of aqueous solution; b) providing a well comprising: i) an upper organic phase, ii) a lower aqueous phase, and iii) a well electrode extending into the lower aqueous phase, wherein at least one of the aqueous solution, the lower aqueous phase, and the upper organic phase comprise lipids, and wherein the dro…

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What does patent US9068280B2 cover?
The invention relates to methods and devices for forming and measuring lipid bilayers, for example, by joining lipid monolayers that self-assemble at the interface of aqueous and organic phases using sessile aqueous droplets in contact with a measurement electrode. At least one of the aqueous solution, the lower aqueous phase, and/or the upper organic phase comprise lipids. This abstract is int…
Who is the assignee on this patent?
Poulos Jason L, Schmidt Jacob J, Univ California
What technology area does this patent fall under?
Primary CPC classification C40B50/08. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jun 30 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).