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Gene expression signature for classification of kidney tumors
US9068232B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9068232-B2 |
| Application number | US-201213412020-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 5, 2012 |
| Priority date | Aug 6, 2008 |
| Publication date | Jun 30, 2015 |
| Grant date | Jun 30, 2015 |
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Abstract
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The present invention provides a method for classification of kidney tumors through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.
First claim
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The invention claimed is: 1. A method for distinguishing between oncocytoma, clear cell renal cell carcinoma (RCC), papillary (chromaphil) RCC and chromophobe RCC in a human subject with renal cancer, the method comprising: (a) obtaining a kidney tumor sample from the human subject; (b) determining an expression profile in said sample of SEQ ID NOS: 1-24 by contacting the sample with probes that hybridize to each of SEQ ID NOS: 1-24, wherein each probe comprises the complement o…
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Chemistry & Metallurgy · mapped topic
Physics · mapped topic
Chemistry & Metallurgy · mapped topic
Physics · mapped topic
- C12Q1/6886Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US9068232B2 cover?
- The present invention provides a method for classification of kidney tumors through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.
- Who is the assignee on this patent?
- Rosenfeld Nitzan, Spector Yael, Friedman Eddie, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6886. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 30 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).