Peptides with vasodilatory and/or diuretic functions
US-2019211071-A1 · Jul 11, 2019 · US
US9067973B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9067973-B2 |
| Application number | US-201314079144-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 13, 2013 |
| Priority date | Feb 21, 2007 |
| Publication date | Jun 30, 2015 |
| Grant date | Jun 30, 2015 |
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Official abstract text for this publication.
The present invention provides peptides having an amino acid sequence as set forth in SEQ ID NO: 19, 22, 30, 34, 344, 358, 41, 44, 46, 48, 78, 376, 379, 80, 100, 101, 110, 111, 387, 112, 394, 114, 116, 117, 121, 395, 133, 135, 137, 426, 143, 147, 148, 149, 150, 152, 153, 154, 156, 160, 161, 162, 163, 166, 174, 178, 186, 194, 196, 202, 210, 213, 214, 217, 223, 227, 228, 233, 254, 271, 272 or 288, as well as peptides having the above-mentioned amino acid sequences in which 1, 2, or several (e.g., up to 5) amino acids are substituted, deleted, or added, provided the peptides possess cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing a disease associated with over-expression of the CDH3, EPHA4, ECT2, HIG2, INHBB, KIF20A, KNTC2, TTK and/or URLC10, e.g. cancers containing as an active ingredient one or more of these peptides. The peptides of the present invention find further utility as vaccines.
Opening claim text (preview).
The invention claimed is: 1. An isolated peptide of less than about 15 amino acids having cytotoxic T cell inducibility, wherein the peptide is selected from the group consisting of: (a) an isolated peptide comprising the amino acid sequences of SEQ ID NO: 114, 116, 117, or 121; (b) an isolated peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 114, 116, 117, or 121, wherein 1 or 2 several amino acids are substituted, deleted, or added.…
Chemistry & Metallurgy · mapped topic
Physics · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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