Heterocyclic derivative and pharmaceutical composition comprising the same
US-9212130-B2 · Dec 15, 2015 · US
Compounds useful as inhibitors of ATR kinase
US9062008B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9062008-B2 |
| Application number | US-201113106337-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 12, 2011 |
| Priority date | May 12, 2010 |
| Publication date | Jun 23, 2015 |
| Grant date | Jun 23, 2015 |
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Abstract
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The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula V: wherein the variables are as defined herein.
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The invention claimed is: 1. A compound selected from the following: 2. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier.
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directly linked by a ring-member-to-ring-member bond · CPC title
- C07D241/20Primary
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directly linked by a ring-member-to-ring-member bond · CPC title
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- What does patent US9062008B2 cover?
- The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates…
- Who is the assignee on this patent?
- Charrier Jean-Damien, Durrant Steven John, Young Stephen Clinton, and 5 more
- What technology area does this patent fall under?
- Primary CPC classification C07D241/20. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 23 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).