Compositions and methods for treatment of edema
US-12144805-B2 · Nov 19, 2024 · US
US9062001B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9062001-B2 |
| Application number | US-201414266048-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 30, 2014 |
| Priority date | Jun 20, 2007 |
| Publication date | Jun 23, 2015 |
| Grant date | Jun 23, 2015 |
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Disclosed herein are substituted N-Aryl pyridinone fibrotic inhibitors and/or collagen infiltration modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
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What is claimed is: 1. A compound having the structural formula: 2. The compound as recited in claim 1 , wherein each of said positions represented as D has deuterium enrichment of at least 98%. 3. The compound as recited in claim 1 , wherein each of said positions represented as D has deuterium enrichment of at least 90%.…
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