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Cross-linkers and their uses
US9061995B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9061995-B2 |
| Application number | US-201314080377-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 14, 2013 |
| Priority date | Apr 30, 2008 |
| Publication date | Jun 23, 2015 |
| Grant date | Jun 23, 2015 |
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Abstract
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Charged or pro-charged cross-linking moieties and conjugates of cell binding agents and drugs comprising the charged or pro-charged cross-linking moieties and method of making the same.
First claim
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What is claimed is: 1. A cell-binding agent-drug conjugate of formula (II) wherein: CB represents a cell-binding agent; D represents a cytotoxic drug linked to the cell-binding agent by a disulfide, thioether, thioester, peptide, hydrazone, ester, ether, carbamate, or amide bond; R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , and R 10 are the same or differen…
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Frequently asked questions
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- What does patent US9061995B2 cover?
- Charged or pro-charged cross-linking moieties and conjugates of cell binding agents and drugs comprising the charged or pro-charged cross-linking moieties and method of making the same.
- Who is the assignee on this patent?
- Immunogen Inc
- What technology area does this patent fall under?
- Primary CPC classification A61K31/5365. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jun 23 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).