Indene derivatives and uses thereof
US-10329269-B2 · Jun 25, 2019 · US
US9061981B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9061981-B2 |
| Application number | US-201214236237-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 1, 2012 |
| Priority date | Aug 1, 2011 |
| Publication date | Jun 23, 2015 |
| Grant date | Jun 23, 2015 |
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Disclosed herein are novel di-aromatic compounds of the general formula (I). Also pharmaceutical compositions comprising the novel compounds and the use of the novel compounds in treatment and prevention of diseases and disorders related to estrogen receptors are disclosed. Furthermore, methods for treating and preventing diseases and disorders related to estrogen receptors by administration of the novel compounds are disclosed.
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The invention claimed is: 1. A compound of formula (I): as one of a single isomer, a mixture of isomers and a racemic mixture of isomers; or one of a solvate and polymorph thereof, or one of a metabolite and prodrug thereof, or a pharmaceutically acceptable salt thereof, wherein, in the Formula (I), R is selected from the group consisting of hydrogen, C 1-6…
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