Radiomic signature of a perivascular region
US-2024404058-A1 · Dec 5, 2024 · US
US9060995B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9060995-B2 |
| Application number | US-201414301799-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 11, 2014 |
| Priority date | Jan 26, 2012 |
| Publication date | Jun 23, 2015 |
| Grant date | Jun 23, 2015 |
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Embodiments of the invention relate to the use of a melatonin agonist in the treatment of free running circadian rhythms in patients, including light perception impaired patients, e.g., blind patients, and to methods of measuring circadian rhythm.
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What is claimed is: 1. A method of entraining a light perception impaired patient suffering from Non-24-Hour Sleep-Wake Disorder to a 24-hour sleep-wake cycle in which the patient awakens at or near a target wake time following a daily sleep period of approximately 7 to 9 hours, wherein the patient is being treated with fluvoxamine, the method comprising: (A) discontinuing the fluvoxamine treatment and then (B) orally treating the patient with 20 mg of tasimelteon once daily bef…
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