Pharmaceutical compositions and treatment of genetic diseases associated with nonsense mediated RNA decay
US-9216180-B2 · Dec 22, 2015 · US
US9060993B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9060993-B2 |
| Application number | US-55622004-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 7, 2004 |
| Priority date | May 9, 2003 |
| Publication date | Jun 23, 2015 |
| Grant date | Jun 23, 2015 |
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Methods of treating individuals identified as having cancer using ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of inducing apoptosis in cancer cells using an ATP citrate lyase inhibitor and/or tri-carboxylate transporter inhibitor are disclosed. of treating an individual who has cancer comprising the steps of identifying the cancer as having a high rate of aerobic glycolysis, and administering an ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of treating individuals who have cancer using compounds that inhibit the expression of ATP citrate lyase or tricarboxylate transporter are disclosed. Methods of identifying a compound with anticancer activity are disclosed.
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What is claimed is: 1. A method of treating an individual who has cancer that comprises cancer cells that have a high rate of aerobic glycolysis, the method comprising the steps of: identifying said cancer as a cancer that comprises cancer cells that have a high rate of aerobic glycolysis, wherein said cancer is determined to be a cancer that comprises cancer cells that have a high rate of aerobic glycolysis by PET imaging using 18 fluoro-deoxyglucose, and subsequently administ…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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