Compositions and methods for treating cancer

US9060993B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9060993-B2
Application numberUS-55622004-A
CountryUS
Kind codeB2
Filing dateMay 7, 2004
Priority dateMay 9, 2003
Publication dateJun 23, 2015
Grant dateJun 23, 2015

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Methods of treating individuals identified as having cancer using ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of inducing apoptosis in cancer cells using an ATP citrate lyase inhibitor and/or tri-carboxylate transporter inhibitor are disclosed. of treating an individual who has cancer comprising the steps of identifying the cancer as having a high rate of aerobic glycolysis, and administering an ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of treating individuals who have cancer using compounds that inhibit the expression of ATP citrate lyase or tricarboxylate transporter are disclosed. Methods of identifying a compound with anticancer activity are disclosed.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating an individual who has cancer that comprises cancer cells that have a high rate of aerobic glycolysis, the method comprising the steps of: identifying said cancer as a cancer that comprises cancer cells that have a high rate of aerobic glycolysis, wherein said cancer is determined to be a cancer that comprises cancer cells that have a high rate of aerobic glycolysis by PET imaging using 18 fluoro-deoxyglucose, and subsequently administ…

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What does patent US9060993B2 cover?
Methods of treating individuals identified as having cancer using ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of inducing apoptosis in cancer cells using an ATP citrate lyase inhibitor and/or tri-carboxylate transporter inhibitor are disclosed. of treating an individual who has cancer comprising the steps of identifying the cancer as having a h…
Who is the assignee on this patent?
Thompson Craig B, Bauer Daniel, Hatzivassiliou Georgia, and 1 more
What technology area does this patent fall under?
Primary CPC classification A61K31/34. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jun 23 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).