Acylamino-substituted fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals
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Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9051280B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9051280-B2 |
| Application number | US-201213546434-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 11, 2012 |
| Priority date | Aug 13, 2010 |
| Publication date | Jun 9, 2015 |
| Grant date | Jun 9, 2015 |
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Abstract
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The present invention relates to tetraline and indane derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such tetraline and indane derivatives, and the use of such tetraline and indane derivatives for therapeutic purposes. The tetraline and indane derivatives are GlyT1 inhibitors.
First claim
Opening claim text (preview).
We claim: 1. A compound of formula (I) wherein A is a 5- or 6-membered ring; R is R 1 —W-A 1 -Q-Y-A 2 -X 1 —; R 1 is hydrogen, C 1 -C 6 -alkyl, C 3 -C 12 -cycloalkyl-C 1 -C 4 -alkyl, halogenated C 1 -C 6 -alkyl, tri-(C 1 -C 4 -alkyl)-silyl-C 1 -C 4 -alkyl, hydroxy-C 1 -C 4 -alkyl, C 1 -C 6 -alkoxy-C 1 -C 4 -alkyl, amino-C 1 -C 4 alkyl, C 1 -C 6 -a…
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Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C07D233/84Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9051280B2 cover?
- The present invention relates to tetraline and indane derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such tetraline and indane derivatives, and the use of such tetraline and indane derivatives for therapeutic purposes. The tetraline and indane derivatives are GlyT1 inhi…
- Who is the assignee on this patent?
- Lange Udo, Amberg Wilhelm, Ochse Michael, and 5 more
- What technology area does this patent fall under?
- Primary CPC classification C07D233/84. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).