4-[-2-[[5-methyl-1-(2-naphtalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine hydrochloride polymorphs and solvates

US9051275B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9051275-B2
Application numberUS-201113577078-A
CountryUS
Kind codeB2
Filing dateFeb 4, 2011
Priority dateFeb 4, 2010
Publication dateJun 9, 2015
Grant dateJun 9, 2015

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Abstract

Official abstract text for this publication.

The present invention relates to polymorphs and solvates of the hydrochloride salt of 4-[2-[[5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine (P027), processes for their preparation, and to pharmaceutical compositions comprising them.

First claim

Opening claim text (preview).

The invention claimed is: 1. A solid polymorphic or solvated form of the hydrochloride salt of 4-[2-[[5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine selected from the group consisting of: a) a polymorphic phase I form having a X-ray powder diffraction pattern showing characteristic peaks at a reflection angle [2θ in degrees] of about 5.9, 8.1, 11.3, 11.7, 14.2, 15.1, 15.8, 16.3, 16.8, 17.8, 18.1, 18.6, 19.8, 20.9, 21.9, 22.8, 23.0, 23.2, 23.6, 23.9, 24.3, 25.0, 2…

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What does patent US9051275B2 cover?
The present invention relates to polymorphs and solvates of the hydrochloride salt of 4-[2-[[5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine (P027), processes for their preparation, and to pharmaceutical compositions comprising them.
Who is the assignee on this patent?
Berenguer Maimó Ramón, Medrano Rupérez Jorge, Benet Buchholz Jordi, and 3 more
What technology area does this patent fall under?
Primary CPC classification C07D231/22. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).