Oral solid preparation comprising aripiprazole and method for producing oral solid preparation comprising aripiprazole

US9051268B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9051268-B2
Application numberUS-201414264693-A
CountryUS
Kind codeB2
Filing dateApr 29, 2014
Priority dateApr 30, 2013
Publication dateJun 9, 2015
Grant dateJun 9, 2015

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  1. Title

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  2. Abstract

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  4. Key dates

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  5. First independent claim

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

[Object] An object of the present invention is to provide an oral solid preparation that can be produced in a simpler manner than conventional methods, that exhibits high bioavailability and high dissolubility even in persons having low stomach acid, and that can also ensure dissolubility after being allowed to stand for a certain period of time. Another object is to provide a simple method for producing the oral solid preparation. [Means for Achieving the Object] The present invention relates to an oral solid preparation comprising, as an active ingredient, a finely milled crystal obtained by milling an aripiprazole hydrate crystal, and a pharmaceutically acceptable carrier, the finely milled crystal having a mean particle size of 15 μm or less; and a method for producing an oral solid preparation comprising the steps of (1) milling an aripiprazole hydrate crystal into a finely milled crystal having a mean particle size of 15 μm or less, and (2) mixing the obtained finely milled crystal with a pharmaceutically acceptable carrier.

First claim

Opening claim text (preview).

The invention claimed is: 1. An oral solid preparation comprising, as an active ingredient, a finely milled crystal obtained by miffing an aripiprazole hydrate crystal, and a pharmaceutically acceptable carrier, the finely milled crystal having a mean particle size of 1 μm to less than 10 μm, and the oral solid preparation being in the form of a tablet, pill, granule, or capsule. 2. The oral solid preparation according to claim 1 , wherein the finely milled cry…

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What does patent US9051268B2 cover?
[Object] An object of the present invention is to provide an oral solid preparation that can be produced in a simpler manner than conventional methods, that exhibits high bioavailability and high dissolubility even in persons having low stomach acid, and that can also ensure dissolubility after being allowed to stand for a certain period of time. Another object is to provide a simple method for…
Who is the assignee on this patent?
Otsuka Pharma Co Ltd
What technology area does this patent fall under?
Primary CPC classification A61K9/14. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jun 09 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).